FLUCURE – Iwan de Esch obtains EU FP7 grant for the development of antiviral drugs
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Dr. Iwan de Esch, associate professor of the Medicinal Chemistry group at VU University Amsterdam, has received 1.1 Meuro funding from the European Commission to continue and expand the highly innovative research to develop novel drugs against influenza.

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Ewald Edink and Iwan de Esch in Journal of American Chemical Society
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Researchers from the Drug Design & Synthesis group led by Dr. Iwan de Esch of the division of Medicinal Chemistry (VU University Amsterdam) have been able to characterize key molecular aspects of ligand-protein binding during a Fragment-Based Drug Discovery (FBDD) project.

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Medicinal Chemistry Team wins world-wide GPCR modeling competition
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Luc Roumen and Chris de Graaf from the Medicinal Chemistry group of VU University Amsterdam recently won a prestigious international challenge in predicting the binding orientation and interactions of a small molecule inhibitor in the CXCR4 chemokine receptor.

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Function of the human receptor for "good" HDL cholesterol unmasked

HDL is known as the “good cholesterol”: it lowers the chance of developing cardiovascular disease. Some families display naturally high levels of HDL in their blood. Research on the underlying causes of genetically high HDL cholesterol is important for the development of new medicines that can increase HDL levels in the blood.

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Research Achievement Award for Professor Meindert Danhof
Meindert Danhof

LACDR Scientific Director, Prof.dr. Meindert Danhof, has been granted the Research Achievement Award in Pharmacokinetics, Pharmacodynamics & Drug Metabolism, during the Pharmaceutical Sciences World Congress in New Orleans on November 15th, 2010.

This award is granted once per two years to top researchers in the field.

Ron de Kloet - Knighted and most Highly Cited!
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On August 25th, during the 7th World Congres on Stress in Leiden, Professor Ron de Kloet, former head of the Division of Medical Pharmacology, was Knighted as "Ridder in de Orde van de Nederlandse Leeuw". He was granted this honor by Mirjam van 't Veld, Mayor of Maarssen, where professor De Kloet lives. 

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Division of Medical Pharmacology presents at FENS
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The Federation of European Neuroscience Societies (FENS) had chosen Amsterdam for its 7th FENS Forum in 2010, July 3-7. FENS Forum is the main European neuroscience meeting (more than 6000 participants), covering disciplines from molecular techniques to clinical studies and from bench to bedside.

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Melly Oitzl in Journal of Cognitive Neuroscience - Corticosteroids operate as a switch between memory systems
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Norman White, McGill University, Canada, July 15, 2010 commented: This study and its follow-up show that stress tends to impair spatial or cognitive memory but probably has no effect on stimulus-response (S-R) or habit memory. The apparent facilitation of S-R behavior may be due to reduced competition from spatial behavior.

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Martine Smit in Science Signaling - A Viral Pathway to Tumor Development
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Human cytomegalovirus (HCMV), a widespread human herpesvirus that persists in a latent form, is associated with pathological processes in immunocompromised hosts and has been implicated in the development of several forms of cancer, including glioblastoma.

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Miriam Peeters wins competition at the Purines 2010 Congress
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PhD-student Miriam Peeters has won the first prize in an international competition for oral communications at the Purines 2010 congress in Tarragona, Spain.  

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Annelien Zweemer to join the 60th Meeting of Nobel Laureates
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Annelien Zweemer is one of the few candidates selected from over 20,000 young scientists world-wide to join the 60th Meeting of Nobel Laureates in Lindau, Germany.

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Progress Report 2009 now available


The LACDR Progress Report 2009 is now available! At the LACDR Spring Symposium on April 13th, 2010, it was presented by Professor Meindert Danhof.

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Andreas Bender wins EFMC Prize for Young Medicinal Chemist in Academia 2010
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Andreas Bender, Assistant Professor in the Medicinal Chemistry Division, is the recipient of the "EFMC Prize for Young Medicinal Chemist in Academia" in 2010.

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Spring Symposium - April 13th 2010
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During this symposium, all current LACDR PhD-Students presented a poster. Additionally, a PhD per division presented his or her research in full during the LACDR PhD Competition. The winners will represent LACDR in the National Competition during the FIGON Medicine Days. Two leaders in the field of Drug Research provided the Key Lectures and afterwards, the LACDR Progress Report 2009 was presented.

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Division of Drug Delivery Technology uses NanoSight Characterization System
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The group of Professor Wim Jiskoot from the Division of Drug Delivery Technology focuses primarily on vaccine delivery and on protein formulation and characterization with respect to immunogenicity. Nanoparticle size and count is vital to this process and it has selected the NanoSight LM20 to aid their programs.

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Division of Medicinal Chemistry battles HIV
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Prof.dr. Herman van Vlijmen from the Division of Medicinal Chemistry Leiden comments on the bases of his research into HIV inhibitors in an interview for the Leiden University Faculty of Science.

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Laura Heitman is Discoverer of the Year 2009!
Dr. Laura Heitman

Dr. Laura Heitman of the Division of Medicinal Chemistry Leiden is this year's winner of the C.J. Kok People’s Choice Award and was named Discoverer of the Year 2009!

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LACDR Divisions in Amsterdam join AIMMS
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AIMMS (Amsterdam Institute for Molecules, Medicines and Systems) joins forces in basic molecular life sciences at the VU campus to reach fundamental breakthroughs in translational molecular medicine with emphasis on the integrated understanding of biological processes, systems, and networks as well as  the development of new drugs, therapeutics and diagnostics.

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25 Years Bio-Pharmaceutical Sciences: Combined fascination
The anniversary symposium

25 Years ago, the Center for Bio-Pharmaceutical Sciences was founded at Leiden University; one year later, in 1985, the education program of Bio-Pharmaceutical Sciences started. On Friday September 18th, this was celebrated with a Symposium, an anniversary booklet, and a grand party.

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LACDR research in PNAS

Just before the holidays, researchers of the division of Medical Pharmacology published a paper in PNAS in which they reveal an important factor in the brain’s response to stress (PNAS 2009,  106(19):8038-42).

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